In the early 1990s, there was a show called "In Living Color" which lead to the rise of eventual stars such as Jim Carrey.
(Yes, I know he was in "The Duck Factory" before that, but I would assume most people heard of him through ILC)
Anyway, there was one skit that involved Oprah back when she was battling her weight--a rather cruel shot at her looking back at it. During the sketch, she talked to her guests while eating and holding food. At the end, she just starts inflating and she floats up and explodes offscreen. I managed to find the inflation part of the skit:
https://www.youtube.com/watch?v=7bmDLT6tAWc
I hope you enjoy this trip down memory lane if you're old enough the remember this show.